The French referee François Letexier will officiate Bayer Leverkusen-Atalanta, the first leg of the 2021-2022 UEFA Europa League Round of 16. His assistants will be Cyril Mugnier (FRA) and Mehdi Rahmouni (FRA), fourth official: Jérémie Pignard (FRA), V.A.R. Jérôme Brisard (FRA), A.V.A.R. Delajod Willy (FRA).